Tramezzino Piemontese is a type of tramezzino sandwich made with soft pancarré triangles that are filled with various ingredients. The tramezzino was invented by Angela De Michelis and her husband Onorino Nebiolo in 1926, who decided to serve their take on English and American tea sandwiches at their Caffé Mulassano in Turin.

Initially, tramezzino Piamontese was filled with butter and anchovies, while the bread was not toasted and was crustless. Today, at Caffé Mulassano, there are about 30 different types of tramezzino. The most popular ones are the tramezzino with lobster, the one with truffles, the one with veal in tuna sauce, and the one with bagna cauda.