This plantain-based casserole is a staple in Puerto Rican and Dominican cuisine. It consists of sliced or mashed plantains that are layered with minced meat. The meat used in the dish is usually the Puerto Rican version of picadillo—a hearty stew prepared with a combination of ground meat and tomato sauce, while the common additions often include shredded cheese or green beans.

Pastelón can be enjoyed as the main course or a filling side dish. It also goes under the name piñon.

Mexico's interpretation of lasagna is called pastel Azteca – a popular baked dish consisting of layered corn tortillas with shredded chicken, cheese, and salsa in between. The dish is traditionally prepared for birthdays and festivities since it can be made a day in advance.

Hot chiles are often added for spiciness, while common accompaniments to the dish include fresh salads or refried beans.

Baked ziti is a casserole-type dish consisting of tubular pasta called ziti that is baked with a variety of other ingredients, mostly chunky sauces, cheese, meat, and vegetables such as mushrooms, peppers, and onions. The dish is considered a hybrid of Italian and American cuisines, basically an Americanized variety of a typical Italian dish, pasta al forno, which is commonly compared to baked ziti.

The casserole is often served as a casual appetizer, cut into big slices, and it is best accompanied by a bowl of green salad. However, it can also be served as a meal on its own, making it a great comfort food for a rainy afternoon. Interestingly, the dish was especially popularized when it appeared in an episode of the hit TV show The Sopranos as one of the favorite dishes of Tony Soprano's wife, Carmela.

Contrary to its name, funeral potatoes are the ultimate comfort food, a cheesy au gratin potato casserole that is synonymous with the state of Utah and The Church of Jesus Christ of Latter-Day Saints. It consists of cubed potatoes, cheese, onions, cream soup or sauce, sour cream, and a topping of butter and cornflakes or crushed potato chips.

The dish is commonly prepared by the members of the Church to comfort grieving relatives after a loved one's funeral, so it is not just an ordinary dish, but also a sign of care, love, and compassion. Although funeral potatoes started as a dish intended for funerals, today it is a common side dish that can be served at any time. 

Frito pie is a cheap, hearty, and highly caloric dish consisting of chili, crunchy corn chips (especially the Fritos brand variety), cheese, and onions. It is a popular meal in Southern and Midwestern parts of the United States, and can be found at numerous state fairs and high school football games.

Although it can be made in a casserole dish, unusually, it is most often prepared in a Fritos corn chip bag, with a number of toppings. The origins of the dish are yet unclear, but it is believed that it was invented in Mexico as a popular food at fiestas before it spread to the United States. 

Hotdish is a Midwestern food icon that is especially popular in the states of Minnesota and North Dakota. Any casserole served hot in a single dish can be called hotdish, and it usually consists of starches such as potatoes or pasta, meat (often ground beef), vegetables, and canned soup (typically cream of mushroom soup).

The first recipe is found in the 1930s Grace Lutheran Ladies Aid Cookbook, but in 1934, Campbell company mixes things up with their canned soups which became the base for most hotdish varieties. The dish originated from the Midwestern farmers who needed to feed their large families, while another theory suggests that it originates from the Norwegian word varmrett, meaning warm dish, due to the fact that there are many Norwegians living in the region. 

Salmon pie is a delicious, comforting, and inexpensive dish from the Canadian region of Québéc. It consists of a pie crust that is filled with a combination of mashed potatoes and cooked salmon, along with spices and other ingredients such as black pepper, parsley, thyme, eggs, and onions, depending on the varieties.

It is then baked until golden brown in color, and when it is served, salmon pie can be additionally garnished with a few dollops of sour cream.

This is not your ordinary mac & cheese. What differentiates the Haitian makawoni au graten (also spelled macaroni au gratin) from mac & cheese are the noodles – there are no elbow macaroni here, since they are replaced by larger pasta types such as rigatoni and penne, along with some unusual flavorings such as mayonnaise, Worcestershire sauce, mustard, and white pepper.

All of the ingredients are typically placed in a casserole dish and sprinkled with grated cheese such as parmesan or cheddar. Some cooks like to add other flavorful additions such as ham or shredded chicken. It is said that makawoni au graten is best consumed during the colder seasons as it is a typical comfort food dish.

Pâté chinois is a popular Quebec dish consisting of a layer of ground beef, a layer of whole or creamed corn, and another layer of mashed potatoes on top. This comfort food staple can be found throughout most cafeterias in Quebec, where it is traditionally served with tomato ketchup on the side.

The name of the dish means Chinese pie, and it is believed that it was invented during the building of the Canadian railway in the 19th century by Chinese cooks, who adapted it from the famous shepherd's pie.